Both Forth Bridges

St. Louis Clinical Trials

St. Louis, MO

St. Louis Clinical Trials Overview

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Investigators

Daniel Gruener, MD, is the Vice President of Medical and Scientific Affairs. He is board certified by the American Academy of Psychiatry and Neurology and by the American Academy of Pain Management. He has conducted more than 250 clinical trials in Pain, Addiction, Opioid Induced Constipation, Schizophrenia, Bipolar, Depression, Anxiety, Sleep Disorders, Alzheimer’s Disease, Hepatitis B and C, Diabetes and Smoking Cessation. Dr. Gruener has been a thought leader in pain for more than 20 years and has served as a board member of the American Pain Society. Additionally, he has written several books, and most significantly, he co-authored a textbook on pain and is the senior editor for Pain Control in the Primary Care Setting, published by the APS, which was the standard of care for several years.

Rick Mofsen, DO, founded St. Louis Clinical Trials in 1998 and currently serves as Chief Medical Officer for Evolution Research Group. He is board certified by the American Osteopathic Board of Neurology and Psychiatry as well as by the American Academy of Pain Management. Dr. Mofsen had been an investigator on 250 CNS and pain trials. He maintains an academic appointment as Assistant Clinical Professor in the Department of Psychiatry at St. Louis University School of Medicine. Dr. Mofsen earned his doctorate degree from the University of Osteopathic Medicine and Health Sciences in Des Moines, Iowa and completed a residency in psychiatry at the University Hospital, State University of New York at Stony Brook. In 1993, Dr. Mofsen founded
Long-Term Psychiatric Management. He currently serves as an advisor to this group. Long-Term Psychiatric Management provides psychiatric consultation and management to more than 100 long-term care and residential facilities in the St. Louis area, and is a primary recruitment source for St. Louis Clinical Trials research programs.

St. Louis Clinical Trials

St. Louis Clinical Trials is a proven and trusted resource for the conduct of complex Phase Ib/IIa studies in Schizophrenia, Major Depressive Disorder, Bipolar Mania, Alzheimer’s disease, Addiction and Pain Management. The research staff is proficient in all standard rating scales and is highly experienced in the conduct of specialized and complex study designs, which include cardiac monitoring (TQT/ QTc), polysomnography (PSG), intensive pharmacokinetic sampling and qEEG. The site’s recruitment team has developed a solid infrastructure for identifying quality research subjects throughout the greater St. Louis region, resulting in meeting and exceeding enrollment targets on the vast majority of its trials.

Facility

A private, inpatient and outpatient research facility, St. Louis Clinical Trials is focused in Phase I-III clinical trials in a variety of therapeutic indications. The purpose built, 55-bed facility is fully equipped, secure, locked and supported by highly experienced MDs, DOs, Nurse Practitioners, Paramedics, Patient Care Technicians, CRCs, Registered Pharmacists (PharmD), Laboratory Technicians and Regulatory Specialists. The facility, built for the comfort of research subjects, has an exercise area, TV, video games, internet access, game room and other amenities.

The facility maintains a compounding pharmacy with an enclosed HEPAfilter hood; a double-locked, limited access drug storage room with a 24-hour monitoring system; an IATA and CLIA certified processing laboratory; and -20 degree and -70 degree sample storage. ECGs are performed at the clinic and radiology facilities (X-ray, PET, CT, MRI, fMRI) are located nearby. In addition, St. Louis Clinical Trials has formed a relationship with The Center for Clinical Imaging Research (CCIR) at Washington University where highly specialized imaging studies such as fMRI and PET are now performed. This Medical Services Agreement gives SLCT access to a variety of services available only at a select few locations worldwide. The research clinic has dedicated monitor rooms with high-speed internet for remote data entry access, on-site long-term storage, a conference room, lobby waiting area and free parking. A central IRB is utilized for all regulatory submissions.

Site Contact
Erica Ridolfi

Institutional Review Board
Central

Contact
info@cnssites.com
+1-908-756-4411

Staffing
35
Staff Members
  • 1 Site Director/Nurse Practioner
  • 4 Sub-Investigators
  • 5 Raters
  • 7 Research Coordinators
  • 5 ACLS Certified Paramedics
  • 1 Inpatient Nurse
  • 8 Patient Care Technicians
  • 1 Pharmacist
  • 3 Recruitment Staff
Patient Database
15,500
Total Number of Subjects
  • 5,500 Schizophrenic Subjects
  • 3,500 Depressed Subjects
  • 2,000 Bipolar Subjects
  • 1,500 Anxiety Subjects
  • 2,500 Alzheimer's Subjects
  • 500 Addiction Subjects
Study Experience
455
Total Studies
  • 65 Phase I/Ib
  • 385 Phase II/III
  • 185 Schizophrenia (Acute/Stable)
  • 10 Addiction
  • 55 Bipolar
  • 60 Depression
  • 27 Alzheimer's Disease
  • 25 Pain
  • 5 Diabetes
  • 13 Hepatitis B & C
  • 5 Smoking Cessation