See what our clients are saying about ERG...

"MCRC has worked with our team for many years, across multiple programs. Always with great quality in data and patient oversight"
"I appreciate your team's effort to make this possible. Fantastic!"
"I wanted to tell you that I think you are all amazing! All of you have been so patient with us and always giving us whatever it is we asked for...and always so quickly! Thank you."
"This study will be a success because of all of you."
It was a pleasure working together with all of you at TWCG and the individuals at St. Louis Clinical Trials on this project."
"Thank you again for your efforts in achieving this milestone"
"I wanted to take a moment to express my appreciation to the CPMI leadership team as well as your pharmacy team. The formulation involves many steps that could easily result in confusion during preparation, but they all executed everything extremely well and should be commended."
"The team was organized, professional and highly competent. I left the training having total confidence in the team, and after witnessing their performance yesterday, my confidence only increased."
"We couldn't have done this without Evolution!"
On behalf of our trial team, I would like to thank you for the great enthusiasm you put in enrolling subjects in our study with the highest data quality.

About Us

Evolution Research Group, LLC (ERG) is the largest, independent clinical research site company in the U.S., and the leader in early and late phase CNS Study execution. ERG’s portfolio of 12 fully owned and operated clinical research units allows clients access to more than 400 beds, 3 surgical centers, state-of-the-art imaging, KOLs in multiple therapeutic specialties, and an affiliate member network of 12 high quality, experienced sites. ERG has a proven track record of executing complex trials in specialized an diverse populations across all age groups. ERG is one of the only site groups that has a pediatric PK unit with the expertise to handle CNS populations.

ERG’s account directors, along with our clinical, operational, recruitment, quality and administration teams work collaboratively with clients to ensure study objectives in a timely fashion.

Although ERG is a fully-integrated platform, it has maintained the local identity of its research sites. Patient engagement is a defining core competency that unites out networks, both portfolio and affiliate members. ERG’s outreach to patients results in delivery of high quality study data, but begins with understanding first hand their unmet medical needs, seeking input on protocol feasibility and providing education and awareness of the risks and benefits of clinical trial participation. By partnering with patients and advocates throughout the development process, ERG improves the quality and conduct of clinical trials for both the sponsors and the trial participants. We are proud to contribute to the delivery of life-changing new medicines in multiple therapeutic areas.

Our network is comprised of 24 clinical research sites:

  • 12 Inpatient units (with >400 beds)
    • Clinical Pharmacology
    • Clinical Research
    • Pediatric and Adolescent with PK Ward
    • Specialty Post-OP Pain Clinics
  • 29 Outpatient Units

Our Expertise

The Evolution Research Group network of Portfolio Sites and Affiliate Sites has access to subjects and research experience with these specialized populations and healthy volunteers:

CNS Populations

  • Psychiatry: Schizophrenia, Bipolar Disorder, Addiction (alcohol, cocaine, nicotine), Opioid Use Disorder, Depressive Disorders, ADHD, Anxiety Disorders, Eating Disorders, PTSD, OCD (adult, adolescent, and pediatric in most indications)
  • Neurology: Alzheimer’s Disease, Multiple Sclerosis, Parkinson’s Disease, Essential Tremor, Sleep Disorders (insomnia, narcolepsy, RLS, apnea), Tourette’s Syndrome (adult and adolescent), Huntington’s Disease, Tardive Dyskinesia, Epilepsy, Autism
  • Pain: Post-Op Pain (breast augmentation, abdominoplasty, bunionectomy, hernia repair, TKA/THA, bariatrics, DFU procedures), PHN, Fibromyalgia, OA, DPN, Gout, CRPS, Migraine

Healthy and Non-CNS Populations:

  • Healthy Volunteers: First-in-Human, First-to-File, PK/PD, SAD/MAD, DDI, FE, BA/BE, QTc/TQT
  • Renal Insufficiency
  • Geriatric and Healthy Geriatric
  • Tobacco Users
  • Smokers
  • Vaccine
  • Endocrinology: Diabetes, Obesity
  • Post-Menopausal
  • Sexual Dysfunction Disorders
  • Hepatic Impairment: Hepatitis, NASH, CLFD
  • Podiatry: DFU, Tinea Pedis, Onychomycosis, Plantar Fasciitis, Morton’s Neuroma, Achilles Tendonitis
  • Dermatology
  • Gastrointestinal
  • Respiratory
  • Cardiovascular Disorders

Why Choose Us

ERG’s Business Development Team has been involved in the placement and execution of hundreds of phase I-IV clinical trials within its established research network.  While each individual network site has unique capabilities and access to varying types of patient populations, the capabilities of the network as a whole can be broken down into eight (8) broad areas of specialization.



General Consulting

Protocol Design. Key Opinion Leaders. Budget Planning.

Network of Clinical Research Sites

Evolution Research Group, LLC, is comprised of inpatient and outpatient, early and late phase research units, is focused on conducting simple and highly complex trials in psychiatric and neurologic disorders, pain indications, addiCtions, sleep disorders, diabetes, NASH, renal & hepatic, tobacco, among others

Scientific Advisory Boards

The team at Evolution Research Group is now offering its clients Scientific  Advisory Board planning and implementation services.

Vendor Resources

Selecting the right vendor for a clinical development program is difficult task. Throughout our history, Evolution Research Group has worked with most clinical research vendors and have a thorough knowledge of available resources.

Client Testimonials

Dr. Hudefi, Nichole and the entire team at Woodland Research Northwest have been a pleasure to work with. The attention to detail in this complex clinical trial was critical to its successful execution. The identification of proper patients and the number randomized significantly contributed to meeting our study timelines. The site's overall performance provided us with a high level of confidence and we would not hesitate to work with them in the future.
ERG’s robust Business Development group identified us as a Sponsor executing a trial in the same population from which ERG recently completed another study. Essentially, ERG had patients with our target indication waiting for the next trial opportunity. From contract to screening, ERG’s seamless start-up process led to the successful activation of five clinical sites in one month! In addition to start-up, their central recruitment team developed a customized plan to fit our enrollment needs with highly visible, timely support from senior management. ERG’s motivation and collaborative nature has made them an absolute pleasure to do business with. We have an exceptionally high level of confidence that they will deliver complex clinical studies on schedule.
"You have all been a pleasure to work with. I have appreciated your professionalism and diligence. There is more work to be done for us at XXXX, and the anxiety will continue a bit longer for some, but due to CPMI’s significant contribution a lot of the weight has been removed."
"I have collaborated with Lori Wright and many of her investigators for over 10 years. I have always found Lori to be remarkably effective. She has a keen understanding of specific trial needs as well as the capabilities and capacity of the investigators she represents."
"For more than 5 years, I have been relying on Lori Wright for critical advice on CNS clinical trial sites. Her unrivaled insights into investigator qualifications, capacity, and readiness have made her the most important go to consultant for clinical trial outfitting in the industry. We have come to depend on her high-value professional clinical site consultations as part of our routine preparations for both new studies and rescue operations"
Working with Lori Wright and the group of clinical research sites she represents is one of the easiest decisions I make when executing a CNS trial. The principal investigators are among the best in the industry and are able to make valuable contributions to development programs by thoughtfully considering scientific issues and generating quality data. Lori provides an operational advantage by ensuring capability prior to commitment, facilitating start up and remaining accountable through study close out.